Prader–Willi Syndrome (PWS)
Condition Description
A genetic disorder that causes obesity, intellectual disability, and shortness in height.
Prader-Willi syndrome is a genetic disorder usually caused by deletion of a part of chromosome 15 passed down by the father.
The most common symptoms of Prader-Willi syndrome are behavior problems, intellectual disability, and short stature. Hormonal symptoms include delayed puberty and constant hunger leading to obesity.
Active Trials
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TRIAL TITLE: This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome.
DESCRIPTION: The primary objective of this study is to evaluate the efficacy of pitolisant in treating excessive daytime sleepiness (EDS) in patients ≥6 years of age with Prader-Willi syndrome.
SPONSOR: Harmony Biosciences, LLC
INDICATION: Prader-Willi Syndrome
STUDY PROTOCOL: HBS-101-CL-312
PHASE: 3
STATUS: Active
RECRUITING PATIENTS: Yes