Prader–Willi Syndrome (PWS)
Condition Description
A genetic disorder that causes obesity, intellectual disability, and shortness in height.
Prader-Willi syndrome is a genetic disorder usually caused by deletion of a part of chromosome 15 passed down by the father.
The most common symptoms of Prader-Willi syndrome are behavior problems, intellectual disability, and short stature. Hormonal symptoms include delayed puberty and constant hunger leading to obesity.
Active Trials
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TRIAL TITLE: An Open-Label Study of the Safety, Tolerability, and Pharmacokinetics of Oral NNZ-2591 in Prader-Willi Syndrome
DESCRIPTION: NEU-2591-PWS-001 is an open-label study of the safety, tolerability, and pharmacokinetics (PK) of NNZ-2591 Oral Solution, 50 mg/mL in male and female children and adolescents with PWS ages 4 to 12 years. Participants receive treatment of orally administered NNZ-2591 for a total of 13 weeks.
SPONSOR: Neuren Pharmaceuticals Ltd.
INDICATION: Prader-Willi Syndrome
STUDY PROTOCOL: NEU-2591-PWS-001
PHASE: 2
STATUS: Active
Enrolling: Yes
Upcoming Trials
Past Trials
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TRIAL TITLE: Study of Tesomet With Open-label Extension in Subjects With Prader-Willi Syndrome (PWS)
DESCRIPTION: This study aimed to evaluate the safety and efficacy of Tesomet (tesofensine + metoprolol) in subjects with PWS.
SPONSOR: Saniona
INDICATION: Prader-Willi Syndrome
STUDY PROTOCOL: TM006
PHASE: 2b
STATUS: Completed